Thermoregulatory Response describes the integrated physiological processes, mediated by the autonomic nervous system and endocrine signaling, aimed at maintaining a stable core body temperature despite external thermal challenges. This involves precise control over cutaneous blood flow, sweat gland activity, and basal metabolic rate. Efficient response is vital for preserving enzyme function and overall metabolic stability.
Origin
This concept arises from human physiology and environmental adaptation studies, rooted in the hypothalamus acting as the central thermostat. The ‘response’ involves effector mechanisms like peripheral vasodilation or shivering. Hormones, particularly thyroid hormones, set the baseline metabolic heat production that the system must manage moment to moment.
Mechanism
When exposed to heat, the primary mechanism involves cutaneous vasodilation to increase heat dissipation via radiation and convection, coupled with active eccrine sweating for evaporative cooling. Conversely, cold exposure triggers vasoconstriction to shunt blood away from the periphery and increase metabolic heat production. Endocrine factors modulate the set point and the overall capacity for heat generation or loss.
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