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Therapeutic Window Establishment

Meaning

Therapeutic Window Establishment is the clinical process of identifying the precise range of hormone concentration within an individual’s body that yields the maximum desired therapeutic benefit—such as symptom resolution and functional improvement—while simultaneously avoiding adverse side effects associated with either under-dosing or over-dosing. This window is highly individualized and is defined by the intersection of objective quantitative biomarker tracking and subjective symptom assessment. Successfully establishing this window is the hallmark of personalized, precision hormone therapy. It represents the sweet spot of dosage for optimal patient outcome.