The clinical administration of short chains of amino acids, known as peptides, designed to mimic, enhance, or modulate the function of natural endogenous signaling molecules within the body. This application is precision-focused, often targeting specific receptor subtypes or growth pathways to promote healing or endocrine balance. These agents offer a high degree of specificity in their action.
Origin
The origin lies in biotechnology and biochemistry, where synthetic biology allows for the creation of highly targeted signaling molecules that may be more stable or potent than native hormones.
Mechanism
The mechanism of action is highly specific, depending on the peptide sequence; some may act as agonists on growth hormone secretagogue receptors, while others might modulate insulin sensitivity or inflammatory cytokines. Successful application relies on appropriate receptor binding and subsequent downstream signal transduction, often resulting in trophic effects on tissues like muscle or bone.
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