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Testosterone Suppression

Meaning

Testosterone Suppression is the clinical state where the circulating levels of the primary male androgen, testosterone, are intentionally or unintentionally reduced below the normal physiological range. This suppression is a therapeutic goal in certain medical conditions, such as advanced prostate cancer or precocious puberty, but can also occur as an unintended consequence of various drugs, chronic illness, or hypothalamic-pituitary dysfunction. Unintentional suppression can lead to adverse health consequences, including loss of lean mass, decreased bone density, and impaired libido. Careful monitoring of the HPG axis is essential when this condition is present.