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Testosterone Signal Integrity

Meaning

Testosterone Signal Integrity refers to the uninterrupted and appropriate transmission of the androgenic signal from the point of synthesis to the target cellular receptor, ensuring maximal physiological effect. This encompasses the free fraction of circulating testosterone, its binding affinity to the androgen receptor, and the subsequent efficiency of downstream gene transcription. Maintaining this integrity is vital for anabolic processes, mood stabilization, and maintaining lean body mass in both sexes. A disruption anywhere in this chain compromises overall hormonal efficacy.