Skip to main content

Testosterone Replacement Therapy Stratification

Meaning

Testosterone Replacement Therapy Stratification is the clinical methodology used to categorize patients into distinct risk and benefit groups based on their underlying cause of hypogonadism, existing comorbidities, age, and specific treatment goals prior to initiating TRT. This systematic classification is essential for personalizing the choice of testosterone formulation, dosing regimen, and monitoring frequency, ensuring that the therapy’s potential benefits outweigh the risks for each individual. Proper stratification is the foundation of responsible TRT practice.