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Testosterone Replacement Risks

Meaning

The documented and potential adverse health outcomes associated with the therapeutic administration of exogenous testosterone, primarily in the treatment of clinical hypogonadism or age-related androgen decline. These risks encompass a range of physiological changes, including erythrocytosis (increased red blood cell count), potential cardiovascular implications, sleep apnea exacerbation, and suppression of endogenous testicular function (spermatogenesis). Clinicians must conduct a thorough risk-benefit analysis and closely monitor patients to mitigate these potential complications.