Testosterone Pulsatility Maintenance is the preservation of the natural, rhythmic, pulsatile release pattern of LH from the pituitary, driving corresponding testicular hormone secretion.
Origin
This concept is fundamental to reproductive endocrinology, recognizing that signal pattern is as crucial as signal amplitude.
Mechanism
Maintenance relies on maintaining the appropriate frequency and amplitude of GnRH secretion, which prevents receptor downregulation and ensures sustained downstream androgen production.
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