Skip to main content

Testosterone Optimization Therapy

Meaning

Testosterone Optimization Therapy (TOT) is a clinical treatment strategy involving the administration of exogenous testosterone to restore circulating levels to a physiological range that supports optimal health, vitality, and functional capacity. This therapy is indicated for individuals with clinically diagnosed hypogonadism or significant age-related testosterone deficiency impacting quality of life and metabolic health. The goal is not merely to normalize a single lab value but to alleviate symptoms and restore the anabolic balance necessary for muscle mass, bone density, and cognitive function. TOT requires careful, continuous clinical monitoring of hormone metabolites and hematological parameters.