Testosterone Level Assessment is the clinical procedure for quantitatively measuring the concentration of testosterone in a patient’s blood serum, saliva, or urine. This diagnostic step is foundational for evaluating the functional status of the Hypothalamic-Pituitary-Gonadal (HPG) axis and diagnosing conditions of androgen deficiency or excess. A comprehensive assessment includes measuring total, free, and bioavailable testosterone to provide a complete clinical picture.
Origin
This practice is fundamental to endocrinology, dating back to the development of radioimmunoassay techniques that allowed for the precise measurement of circulating steroid hormones. The term emphasizes the critical role of measurement in clinical decision-making. Accurate assessment is the prerequisite for any informed therapeutic intervention involving androgens.
Mechanism
The primary mechanism involves collecting a biological sample, typically blood, and utilizing laboratory techniques such as immunoassay or liquid chromatography-tandem mass spectrometry (LC-MS/MS) to quantify the hormone molecules. For the most accurate clinical insight, a simultaneous measurement of Sex Hormone-Binding Globulin (SHBG) is often performed, allowing for the calculation or direct measurement of the biologically active free testosterone fraction.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.