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Testosterone Gut Microbiome

Meaning

The Testosterone Gut Microbiome describes the intricate and reciprocal relationship between the circulating levels and metabolism of testosterone and the diverse community of microorganisms residing in the gastrointestinal tract. The gut microbiome significantly influences testosterone by regulating its enterohepatic circulation and producing enzymes that affect its systemic bioavailability. Conversely, testosterone can also modulate the overall composition and functional activity of the gut microbiota. This bidirectional axis is a critical, emerging area of research in hormonal health, linking states of gut dysbiosis to compromised androgen status.