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Testosterone Endogenous Restoration

Meaning

Testosterone Endogenous Restoration is a clinical strategy focused on implementing interventions—including targeted nutritional support, specific exercise protocols, and pharmacological agents—designed to stimulate and maximize the body’s intrinsic production of testosterone by optimizing the hypothalamic-pituitary-gonadal (HPG) axis. This approach is fundamentally distinct from exogenous testosterone replacement therapy, aiming instead to correct the upstream regulatory or metabolic deficits that are suppressing the Leydig cells’ ability to synthesize the hormone. The ultimate goal is to achieve a sustained, physiological level of androgen production without introducing external hormones.