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Testosterone Cessation Effects

Meaning

Testosterone cessation effects refer to the spectrum of physiological and psychological changes that manifest following the abrupt or gradual discontinuation of exogenous Testosterone Replacement Therapy (TRT). These effects can range from transient symptoms like fatigue, mood disturbances, and reduced libido to more pronounced and persistent symptoms associated with hypogonadism. The severity and duration of these effects are highly variable, influenced by the individual’s baseline endogenous testosterone production capacity and the duration of the prior therapy. Clinically managing cessation requires careful planning to mitigate the rebound symptoms of hormonal imbalance.