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Testosterone Biochemistry

Meaning

The comprehensive study of the molecular synthesis, metabolic pathways, transport mechanisms, receptor interactions, and eventual catabolism of the androgen hormone testosterone within the human body. This encompasses the conversion of cholesterol precursors, the regulation by the HPG axis, its binding to Sex Hormone-Binding Globulin (SHBG), its conversion to dihydrotestosterone (DHT) and estradiol, and its genomic and non-genomic signaling effects. Understanding this intricate biochemistry is essential for clinical management.