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Testicular Volume Maintenance

Meaning

Testicular Volume Maintenance is the clinical objective of preserving the physical size and cellular mass of the testes during hormonal interventions that might otherwise cause atrophy. This goal is particularly relevant during exogenous testosterone replacement therapy, which typically suppresses the pituitary’s release of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH). Maintenance is achieved by co-administering agents that mimic or stimulate the action of these gonadotropins, thus preserving the seminiferous tubules and Leydig cell integrity.