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Testicular Reserve

Meaning

Testicular reserve is a clinical concept that quantifies the functional capacity of the testes to produce both sperm (spermatogenesis) and androgens, primarily testosterone, in response to hormonal stimulation. It reflects the overall health and quantity of the testicular germ cells and Leydig cells. Assessing this reserve is crucial in the clinical evaluation of male fertility, hypogonadism, and prior to initiating potentially gonadotoxic therapies.