The physiological process of actively altering the structural integrity and mechanical properties of a tendon, primarily its tensile strength and stiffness, in response to specific loading patterns and hormonal signals. This modulation is a critical adaptive response, enabling tendons to withstand greater force transmission and reducing the risk of strain or rupture. Clinically, it involves therapeutic loading protocols and is influenced significantly by anabolic hormones.
Origin
‘Tenon’ is an archaic or less common spelling/form of ‘Tendon,’ derived from the Greek tenon meaning sinew. ‘Strength Modulation’ refers to the controlled, adaptive change in mechanical properties. This concept is central to orthopedic rehabilitation and sports medicine, rooted in the mechanobiology of connective tissue adaptation.
Mechanism
Mechanical tension from resistance exercise initiates a mechanotransduction cascade within tenocytes, the resident tendon cells. This signaling upregulates the synthesis of collagen, particularly type I collagen, and other extracellular matrix proteins. Anabolic hormones, such as testosterone and growth hormone, further enhance this process by increasing tenocyte proliferation and matrix deposition, leading to a thicker, stiffer, and more robust tendon structure capable of handling greater kinetic loads.
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