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Temporal Biomarker Sequence

Meaning

Temporal Biomarker Sequence is the chronological pattern of changes observed in a series of quantifiable biological indicators, such as circulating hormone levels, metabolic intermediates, or inflammatory cytokines, over a defined period of time. Analyzing this sequence, rather than isolated static measurements, provides critical clinical insight into the dynamic function of the endocrine system, revealing the phase, amplitude, and rhythmicity of hormonal pulses, which are essential for diagnosing conditions like HPA axis dysfunction or circadian disruption. This time-series data offers a superior, functional understanding of physiological adaptation and resilience.