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Telomere Maintenance Signaling

Meaning

Telomere Maintenance Signaling describes the complex intracellular biochemical pathways and molecular mechanisms responsible for regulating the length and integrity of telomeres, the protective caps on the ends of chromosomes. This signaling network is essential for cellular stability and lifespan, primarily involving the regulation of the telomerase enzyme and the cell’s response to DNA damage. Efficient maintenance is a key marker of cellular youth and longevity.