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Telomere Lengthening Therapy

Meaning

Telomere Lengthening Therapy refers to the therapeutic strategies, both conceptual and in development, aimed at actively extending the length of telomeres, the protective caps on the ends of chromosomes, which are a primary biomarker of cellular aging. The clinical goal is to reverse telomere attrition, thereby increasing the replicative capacity of somatic cells and potentially extending the healthspan of tissues. While highly experimental, the pursuit represents a direct intervention into one of the fundamental molecular mechanisms of senescence, promising to improve tissue regeneration and cellular function.