A class of small, biologically active amino acid chains specifically designed or identified to promote the lengthening of telomeres, the protective structures on chromosomes, thereby supporting cellular health and longevity. These peptides function as signaling molecules that can directly or indirectly modulate the activity of the telomerase enzyme or protect telomeres from degradation. They represent a targeted approach within the field of anti-aging medicine.
Origin
This term is a modern development within peptide science and gerontology, based on the fundamental understanding of cellular aging mechanisms. ‘Telomere Extension’ describes the desired biological effect, and ‘Peptides’ identifies the molecular class of the therapeutic agent. This area of research seeks to translate the molecular mechanisms of longevity into clinical applications.
Mechanism
These peptides operate by acting as agonists or modulators of specific intracellular pathways that regulate telomerase activity or the cellular stress response. Some may directly bind to and activate the telomerase enzyme complex, while others might improve the overall cellular environment by reducing inflammation or enhancing DNA repair mechanisms. The ultimate function is to stabilize the genome and extend the replicative lifespan of cells.
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