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Telomere Dynamics Influence

Meaning

Telomere dynamics influence refers to the modulation of the rate of telomere shortening and the maintenance of telomere structure, which are critical determinants of cellular lifespan and genomic stability. Telomeres are the protective caps on the ends of chromosomes, and their progressive shortening acts as a mitotic clock, leading to cellular senescence when a critical length is reached. Therapeutic influence involves interventions designed to slow the rate of loss or, in some cases, promote elongation, thereby extending the replicative capacity of key somatic cells. This modulation is a direct strategy for addressing one of the primary hallmarks of biological aging.