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Tau Protein

Meaning

Tau protein is a crucial microtubule-associated protein primarily found in neurons, where its normal function is to stabilize the internal scaffolding structure of the axon. It plays a vital role in maintaining the integrity of the neuronal transport system, which is essential for communication between brain cells. In pathology, Tau can become hyperphosphorylated and aggregate into neurofibrillary tangles, a hallmark feature of several neurodegenerative diseases, including Alzheimer’s disease.