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Targeted Trophic Factor Delivery

Meaning

Targeted trophic factor delivery is a sophisticated therapeutic strategy focused on administering specific growth-promoting molecules directly to a compromised tissue, most commonly within the central nervous system. Trophic factors, such as Brain-Derived Neurotrophic Factor (BDNF) or Nerve Growth Factor (NGF), are essential for neuronal survival, differentiation, and synaptic plasticity. The goal of this targeted approach is to overcome the blood-brain barrier and achieve high local concentrations at the site of neurodegeneration or injury, minimizing systemic side effects.