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Targeted Neurotrophic Factor Upregulation

Meaning

A therapeutic strategy aimed at increasing the endogenous production or activity of specific neurotrophic factors, which are specialized proteins that support the survival, differentiation, and growth of neurons. Upregulation is pursued to enhance brain plasticity, promote neurogenesis, and protect against neurodegeneration, particularly in areas like the hippocampus and cortex. The approach is considered “targeted” because it seeks to selectively influence specific signaling pathways for maximum cognitive benefit.