The precise delivery of specific biochemical compounds, such as vitamins, cofactors, peptides, or pharmaceutical agents, designed to interact with a known molecular target or pathway within the cell to achieve a desired physiological outcome. This strategy moves beyond broad supplementation to utilize high-specificity agents that modulate enzyme activity, receptor signaling, or gene expression with minimal off-target effects. It is a core principle of advanced, high-precision therapeutic intervention.
Origin
This concept is an adaptation of pharmacology and molecular biology principles for the wellness space, emphasizing specificity and mechanism of action. The term “targeted” highlights the intentional design to influence a specific biological pathway, often one that is known to be compromised in aging or disease. This approach is central to modern, evidence-based nutraceutical and hormonal therapy.
Mechanism
Molecular inputs operate by either acting as direct precursors to a deficient compound, such as providing specific amino acids for neurotransmitter synthesis, or by allosterically modulating the activity of a key enzyme. For example, a targeted peptide might bind to a specific G-protein coupled receptor to amplify the natural pulsatile release of growth hormone. The efficacy relies on the input’s bioavailability and its precise fit with the intended molecular receptor or pathway to generate the correct cellular signaling instruction.
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