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Tamoxifen Risks Men

Meaning

Tamoxifen risks in men refers to the spectrum of potential adverse health consequences associated with the off-label use of Tamoxifen Citrate, a Selective Estrogen Receptor Modulator (SERM), primarily prescribed to men for treating gynecomastia or as an ancillary medication in Testosterone Replacement Therapy (TRT). While Tamoxifen can effectively increase endogenous testosterone and suppress estrogenic effects in breast tissue, its systemic use is associated with risks including visual disturbances, which can be permanent, and an increased risk of thromboembolic events. Furthermore, long-term use can negatively alter lipid profiles and potentially increase the risk of developing cataracts, necessitating careful risk-benefit analysis by the prescribing clinician.