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T3 Conversion Dynamics

Meaning

The complex, rate-limiting physiological process by which the relatively inactive prohormone Thyroxine (T4) is converted into the biologically active thyroid hormone Triiodothyronine (T3) within peripheral tissues, primarily the liver and kidneys. Optimal conversion dynamics are essential for maintaining a healthy metabolic rate, energy production, and mood regulation. Impairment in this process is a common cause of hypothyroid symptoms despite normal TSH and T4 levels.