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T: E2 Ratio

Meaning

The T:E2 Ratio is a critical endocrine biomarker representing the calculated proportion of total or free Testosterone (T) to Estradiol (E2), the primary estrogen, circulating in the body. This ratio is more informative than absolute hormone levels alone, as it reflects the balance between androgens and estrogens, which is vital for maintaining systemic health in both men and women. An imbalance in this ratio can contribute to symptoms ranging from mood disturbances to increased cardiovascular risk.