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Systems Biology Modeling

Meaning

Systems Biology Modeling is an advanced computational and mathematical approach used to analyze and simulate the complex, non-linear interactions among multiple biological components—including genes, proteins, metabolites, and hormones—within a living system. In hormonal health, this practice allows clinicians to visualize and predict how an intervention in one axis, such as thyroid hormone replacement, will cascade and affect other interconnected axes, like the HPG or HPA axes. This methodology moves clinical prediction beyond linear causality to a holistic, network-based understanding.