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Systems Biology in Endocrinology

Meaning

Systems Biology in Endocrinology is an advanced, integrative scientific methodology that analyzes hormonal regulation not as isolated, linear pathways but as a dynamic, complex network of interacting genes, proteins, metabolites, and environmental influences. This approach utilizes computational modeling and high-throughput data integration to understand how perturbations in one endocrine axis cascade and affect the entire biological system. It moves beyond traditional reductionism to fully explain the complex, non-linear relationships that govern hormonal health, metabolic function, and disease susceptibility.