The utilization of computational and mathematical modeling to analyze the complex, non-linear interactions among biological components, such as genes, proteins, and metabolites, within an organism.
Origin
This methodology is a direct outgrowth of genomics and bioinformatics, aiming to understand the emergent properties of biological networks rather than isolated components.
Mechanism
Application involves integrating diverse data sets—genomic, proteomic, metabolomic—to map regulatory pathways, predict system responses to perturbation, and identify leverage points for targeted therapeutic intervention.
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