What is the Origin of Systems-Based Neurology?

This framework evolves from traditional, localized neurology toward a holistic, systems biology model, recognizing the brain's dependence on systemic inputs like thyroid hormones and sex steroids. The term signifies a shift from lesion-centric diagnosis to understanding regulatory network integrity. It acknowledges the CNS as a critical component within the body's larger homeostatic machinery.

What is the Mechanism of Systems-Based Neurology?

The mechanism involves analyzing feedback loops where endocrine status directly influences neurotrophic factor expression, neurotransmitter receptor density, and glial cell function across the entire CNS. For instance, optimizing the hypothalamic-pituitary-adrenal axis directly regulates the neuroinflammatory tone that affects widespread neural communication. Interventions target the systemic drivers of neurological health rather than isolated neural symptoms.

Systems-Based Neurology ∞ Area

Systems-Based Neurology

Meaning

Systems-Based Neurology is an integrative approach to neurological assessment and intervention that views the nervous system not as isolated structures but as a complex, interconnected network influenced profoundly by systemic physiology, particularly the endocrine axis. This perspective demands that neurological function be understood in the context of hormonal balance, metabolic capacity, and systemic inflammation. Clinical evaluation seeks coherence across these interconnected physiological domains. It is the neurology of context.