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Systemic Stress Resilience Quantification

Meaning

Systemic Stress Resilience Quantification is the clinical process of objectively measuring an individual’s capacity to maintain physiological and psychological homeostasis when exposed to various internal or external stressors. This metric moves beyond simply assessing basal stress markers to evaluate the dynamic, adaptive response of the Hypothalamic-Pituitary-Adrenal (HPA) axis, the autonomic nervous system, and the immune system. Quantification often involves dynamic testing, such as measuring cortisol recovery patterns after a challenge or assessing Heart Rate Variability (HRV). A high resilience score indicates a robust, flexible stress response system, which is a critical determinant of healthspan and longevity.