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Systemic Stress Load Quantification

Meaning

Systemic Stress Load Quantification is the clinical process of integrating multiple physiological and biochemical measurements to derive an objective estimate of the cumulative allostatic burden placed upon the body by chronic stressors. This quantification moves beyond assessing individual stress hormones to capture the integrated cost of adaptation across multiple regulatory systems. A high quantified load suggests diminished physiological reserve and increased vulnerability to acute illness or chronic disease progression. We seek to measure the total wear and tear on the homeostatic machinery.