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Systemic Stress Adaptation

Meaning

Systemic Stress Adaptation is the comprehensive, multi-faceted physiological process by which the entire organism adjusts and maintains allostatic stability in response to chronic or repeated physical, psychological, or environmental challenges. This process involves the coordinated modulation of the neuroendocrine, immune, and metabolic systems to ensure survival and functional integrity under duress. Successful adaptation is characterized by a return to baseline function with minimal long-term physiological cost.