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Systemic Signaling

Meaning

Systemic Signaling describes the complex, integrated communication network that utilizes hormones, neuropeptides, cytokines, and metabolites to transmit information and coordinate functional responses across the entire organism. This global communication is fundamental to maintaining homeostasis, regulating metabolism, and ensuring synchronized adaptation to external and internal stressors. It is the body’s comprehensive, long-distance communication infrastructure, ensuring all organs are working in concert for the greater good of the organism.