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Systemic Resilience Factors

Meaning

Systemic Resilience Factors are the composite biological and physiological elements that collectively determine an individual’s capacity to resist, adapt to, and rapidly recover from various physical, psychological, and metabolic stressors. These factors encompass the robustness of the HPA axis, the efficiency of the immune response, the integrity of the mitochondrial network, and the stability of the hormonal milieu. A high degree of systemic resilience is clinically correlated with a slower rate of biological aging and a reduced susceptibility to chronic, stress-induced illnesses. Clinical efforts in longevity medicine are often focused on identifying and optimizing these core resilience factors.