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Systemic Resilience

Meaning

Systemic Resilience is the intrinsic, integrated capacity of an organism’s major physiological systems—most notably the endocrine, immune, and nervous systems—to effectively withstand, adapt to, and rapidly recover from significant internal or external stressors. This crucial metric transcends the health of individual organs, reflecting the robust, coordinated, and efficient function of the body’s entire regulatory network. High systemic resilience is a hallmark of biological youth and a central, measurable objective of advanced longevity-focused medicine.