A class of small, naturally occurring or synthetic amino acid chains used clinically to promote healing, regeneration, and anti-inflammatory responses across multiple organ systems throughout the body. These peptides function as biological signaling molecules, selectively binding to cellular receptors to initiate specific repair cascades and homeostatic restoration processes. Their systemic action allows for broad therapeutic utility in addressing age-related tissue degradation and injury.
Origin
This term emerges from the rapidly advancing field of peptide therapeutics and regenerative medicine, leveraging the body’s endogenous signaling mechanisms. The “systemic” aspect differentiates them from localized treatments, emphasizing their capacity to circulate and act on distant targets.
Mechanism
These peptides operate by mimicking or modulating the action of endogenous growth factors and cytokines, often binding to G-protein coupled receptors or activating specific kinase pathways. Their action typically involves stimulating cellular migration, proliferation, and differentiation, while simultaneously suppressing pro-inflammatory cytokine release and oxidative stress. This dual role promotes tissue healing and restores the microenvironment to a state conducive to regeneration.
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