What is the Origin of Systemic Repair Cycles?

This concept synthesizes the biological processes of autophagy, nocturnal growth hormone release, and circadian-regulated DNA repair into a unified, cyclical framework. The systemic aspect emphasizes the coordinated nature of these repair functions across all major organ systems.

What is the Mechanism of Systemic Repair Cycles?

The cycles are hormonally regulated, primarily by the nocturnal surge of growth hormone and the low levels of insulin characteristic of the fasting and deep sleep state. This hormonal milieu promotes autophagy and facilitates the work of DNA repair enzymes, whose activity is also under circadian control. Ensuring uninterrupted sleep and a sufficient fasting window is paramount to allowing these essential systemic repair mechanisms to execute fully.

Systemic Repair Cycles

Meaning

Systemic Repair Cycles are the recurring, naturally scheduled periods of cellular maintenance, detoxification, and tissue regeneration that occur throughout the body, predominantly during the fasting state and deep sleep. These cycles are critical for clearing damaged proteins, repairing DNA, and restoring hormonal receptor sensitivity, processes essential for longevity and preventing age-related decline. Disruption of these cycles accelerates biological aging.