The precise clinical process of restoring metabolic function, including glucose homeostasis, lipid processing, and energy substrate utilization, to an optimal, highly efficient state across the entire organism. This correction often involves modulating insulin sensitivity, optimizing mitochondrial function, and rebalancing key adipokines and satiety hormones. It addresses the core energy machinery of the body.
Origin
This terminology stems from endocrinology and metabolism, where ‘Metabolic Correction’ signifies fixing dysregulated energy pathways. ‘Systemic’ underscores that the intervention targets the integrated network of metabolic organs rather than a single pathway.
Mechanism
Correction frequently targets insulin receptor signaling, enhancing glucose uptake into muscle and adipose tissue, thereby reducing hyperinsulinemia and subsequent metabolic stress. Furthermore, optimizing the thyroid hormone profile ensures that cellular metabolic rate is appropriately calibrated to support energy expenditure. These actions together restore efficient substrate oxidation, moving the system away from lipogenic storage patterns.
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