What is the Origin of Systemic Inflammation Quelling?

This term originates from clinical immunology and pathology, emphasizing the active suppression or 'quelling' of inflammatory mediators across the entire organism, not just localized sites. It recognizes inflammation as a pervasive systemic disruptor.

What is the Mechanism of Systemic Inflammation Quelling?

Quelling involves multifaceted strategies, including optimizing gut barrier integrity to reduce endotoxin translocation and increasing the synthesis of specialized pro-resolving mediators (SPMs). By modulating cytokine balance and reducing oxidative stress, the body shifts from a chronic inflammatory state back toward immunological and metabolic quiescence.

Systemic Inflammation Quelling

Meaning

Systemic Inflammation Quelling is the comprehensive clinical objective of actively suppressing widespread, chronic inflammatory signaling throughout the body’s tissues and circulation. This low-grade inflammation is a major endocrine antagonist, impairing insulin sensitivity and steroidogenesis. We aim to resolve the underlying inflammatory burden.