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Systemic Inflammation Effects

Meaning

Systemic Inflammation Effects describe the widespread, deleterious consequences on multiple organ systems and complex physiological processes caused by a chronic, low-grade elevation of inflammatory mediators throughout the body. These measurable effects include the significant disruption of essential endocrine signaling, pervasive metabolic dysregulation, increased cellular oxidative stress, and impaired functional capacity across various tissues, with notable impact on the central nervous system and the cardiovascular system. Chronic inflammation is recognized as a profound and significant driver of age-related decline and chronic disease pathology.