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Systemic Inflammation Cognitive Performance

Meaning

Systemic Inflammation Cognitive Performance refers to the negative correlation between chronic, elevated levels of inflammatory markers throughout the body and a measurable decline in various cognitive functions, including sustained attention, memory consolidation, and executive processing. This clinical relationship highlights that peripheral inflammation, originating from sources like visceral adiposity or chronic infection, directly compromises the integrity and function of the central nervous system. It establishes inflammation as a major non-neuronal contributor to age-related cognitive decline.