Skip to main content

Systemic Inflammation Clearance

Meaning

Systemic Inflammation Clearance refers to the active physiological processes responsible for resolving widespread, low-grade inflammation and returning the immune system to a quiescent, homeostatic state. Effective clearance is essential because unresolved inflammation actively suppresses anabolic signaling and contributes to hormonal dysregulation, such as cortisol resistance. This clearance mechanism relies on the timely deactivation of pro-inflammatory pathways and the upregulation of anti-inflammatory regulators. Clinically, we assess clearance efficiency to determine overall metabolic resilience.