The clinical process of identifying, targeting, and correcting underlying suboptimal functional bottlenecks or dysregulations across multiple interconnected biological systems. This approach moves beyond single-symptom treatment to address the root causes of chronic low-grade dysfunction, such as mild mitochondrial impairment, subtle hormonal imbalances, or chronic inflammation. The resolution leads to a measurable, synergistic improvement in overall health and vitality.
Origin
This concept is foundational to functional and systems medicine, recognizing that chronic illness and suboptimal health often stem from interconnected, low-grade dysfunctions rather than a single pathology. The term ‘resolution’ emphasizes the active, therapeutic correction of these underlying functional deficits.
Mechanism
The process begins with advanced diagnostics to map the individual’s “systems biology wiring diagram” and pinpoint areas of inefficiency, such as poor nutrient absorption or sluggish hormone clearance. Interventions are then designed to restore optimal function, perhaps by supporting mitochondrial biogenesis with targeted cofactors or by utilizing specific nutrients to enhance liver detoxification pathways. The resolution is achieved when the cascade of negative downstream effects is halted and the system’s inherent self-regulatory capacity is restored.
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