Systemic Healing Mechanisms are the complex, interconnected biological processes throughout the body that work collectively to repair cellular damage, resolve inflammation, and restore tissue integrity following injury, stress, or illness. These mechanisms include the coordinated efforts of the immune system, the endocrine repair cascade, and cellular regeneration pathways. Optimizing these innate systems is a core principle of regenerative and longevity medicine.
Origin
This term is a conceptual framework in functional and regenerative medicine, combining “Systemic,” indicating body-wide involvement, with “Healing Mechanisms,” referring to the inherent biological processes of repair. It moves beyond localized repair to encompass the body’s total capacity for self-renewal.
Mechanism
The mechanism involves a coordinated endocrine and cellular response, beginning with the initial inflammatory phase which clears damaged cells. This is followed by the proliferative phase, mediated by growth factors like Growth Hormone and IGF-1, which stimulate cell division and extracellular matrix synthesis. The final remodeling phase ensures functional restoration. The efficiency of these mechanisms is highly dependent on nutrient status, hormonal balance, and low oxidative stress levels.
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