What is the Origin of Systemic Functional Integrity?

This term is a core concept in systems biology and functional medicine, emphasizing the interconnectedness of biological processes. It moves beyond the pathology-centric view to a holistic assessment of biological resilience. The etymology emphasizes the 'integrity' or completeness of function across the entire 'system.'

What is the Mechanism of Systemic Functional Integrity?

Maintaining this integrity relies on optimizing the central regulatory axes, such as the Hypothalamic-Pituitary-Adrenal (HPA) and Hypothalamic-Pituitary-Gonadal (HPG) axes, to ensure precise hormonal communication. The mechanism involves reducing chronic inflammation, maintaining genomic stability, and supporting endothelial function across the vascular network. This coordinated approach ensures that all cellular and organ systems receive accurate signals and sufficient resources to perform their roles efficiently.

Systemic Functional Integrity

Meaning

Systemic Functional Integrity is the state of robust, coordinated, and resilient operation across all major organ systems and regulatory networks, including the endocrine, immune, and cardiovascular systems. This integrity is the ultimate measure of health span, signifying that all physiological components are functioning harmoniously and efficiently. A high degree of integrity translates to superior adaptive capacity and reduced susceptibility to age-related disease.