Systemic Feedback Loops

Meaning

Systemic feedback loops are the core regulatory mechanisms within the endocrine system and human physiology where the output of a system acts as an input to influence its own future activity. These loops are essential for maintaining dynamic homeostasis, ensuring that hormone levels and physiological parameters remain within a tightly controlled, healthy range. There are two primary types: negative feedback, which is stabilizing and dampens the original stimulus, and positive feedback, which is destabilizing and amplifies the original stimulus. Disruptions in these intricate loops are the underlying cause of many common hormonal disorders.

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